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1. Le Roux, G.A.C. ; REIS, G. B. ; JESUS, C. D. F. ; GIORDANO, R. C. ; CRUZ, A. J. G. ; Moreira Jr, P.T. ; NASCIMENTO, C. A. O. ; LOUREIRO, L. V. . Cooperative Weblabs: A tool for cooperative learning in chemical engineering in a global environment. Chemical Engineering Education, v. 44, p. 9-12, 2010.
2. NUCCI, Edson Romano ; Cruz, Antonio J. G. ; Giordano, Roberto C. . Monitoring bioreactors using principal component analysis: production of penicillin G acylase as a case study. Bioprocess and Biosystems Engineering (Print), v. 33, p. 557-564, 2010.
3. PINTO, Gilson Alexandre ; GIORDANO, R. L. C. ; GIORDANO, R. C. . Remote engineering for a cheese whey biorefinery: an Internet-based application for process design, economic analysis, monitoring, and control of multiple plant sites. Bioprocess and Biosystems Engineering, v. 32, p. 69-78, 2009.
4. CABRERAPADILLA, R ; PINTO, G ; GIORDANO, R ; GIORDANO, R . A new conception of enzymatic membrane reactor for the production of whey hydrolysates with low contents of phenylalanine. Process Biochemistry, v. 44, p. 269-276, 2009.
5. GALVAO, C ; PINTO, G ; JESUS, CDF ; GIORDANO, R. C. ; Giordano, Raquel L. C. . Producing a phenylalanine-free pool of peptides after tailored enzymatic hydrolyses of cheese whey. Journal of Food Engineering, v. 91, p. 109-117, 2009.
6. Trovati, Joubert ; GIORDANO, R. C. ; Giordano, Raquel L. C. . Improving the Performance of a Continuous Process for the Production of Ethanol from Starch. Applied Biochemistry and Biotechnology, v. 156, p. 76-90, 2009.
7. Santana, Mônica ; Ribeiro, Marcelo P. A. ; Leite, Geisa A. ; Giordano, Raquel L. C. ; Giordano, Roberto C. ; Mattedi, Silvana . Solid-liquid equilibrium of substrates and products of the enzymatic synthesis of ampicillin. AIChE Journal, p. NA-NA, 2009.
8. NUCCI, Edson Romano ; Souza, Vanessa Ribeiro ; Silva, Rosineide Gomes ; Reis, Giann Braune ; Giordano, Raquel Lima Camargo ; Giordano, Roberto Campos ; Cruz, Antonio José Gonçalves . On-line Monitoring of Penicillin G Acylase (PGA) Production Using a Fuzzy Logic Algorithm. Chemical Product and Process Modeling, v. 4, p. 12, 2009.
9. Nucci, E. R. ; CRUZ, A. J. G. ; GIORDANO, R. L. C. ; GIORDANO, R. C. . Monitoring Penicillin G Acylase (PGA) Production Using Principal Component Analysis (PCA).. Computer-Aided Chemical Engineering, v. 27, p. 1629-1634, 2009.
10. Da Silva, A.J. ; Horta, A.C. ; Iemma, M. ; Novo, M.T. ; Zangirolami, T.C. ; Giordano, R. . Production of potential subunit vaccine against swine erysipelas in fed-batch cultures of E. coli BL21(DE3). New Biotechnology, v. 25, p. S223-S223, 2009.
11. GIORDANO, R. C. ; BERTINI JR, J. ; NICOLETTI, M. C. ; GIORDANO, R. L. C. . Online filtering of CO2 signals from a bioreactor gas outflow using a committee of constructive neural networks. Bioprocess and Biosystems Engineering, v. 31, p. 101-109, 2008.
12. RIBEIRO, Marcelo Perencin de Arruda ; PÁDUA, T. F. ; LEITE, O. D. ; GIORDANO, R. L. C. ; GIORDANO, R. C. . Multivariate calibration methods applied to the monitoring of the enzymatic synthesis of ampicillin. Chemometrics and Intelligent Laboratory Systems, v. 90, p. 169-177, 2008.
13. SILVA, Rosineide Gomes da ; PINOTTI, Laura M ; CRUZ, Antônio José Gonçalves da ; GIORDANO, R. L. C. ; GIORDANO, R. C. . Artificial neural networks to infer biomass and product concentration during the production of penicillin G acylase from Bacillus megaterium. Journal of Chemical Technology and Biotechnology, v. 83, p. 739-749, 2008.
14. SILVA, A. J. ; BAPTISTA-NETO, A. ; CILENTO, M. C. ; GIORDANO, R. C. ; ZANGIROLAMI, Teresa Cristina . Bioreactor aeration conditions modulate growth and antigen expression during Erysipelothrix rhusiopathiae cultivation. Applied Microbiology and Biotechnology, v. 79, p. 23-31, 2008.
15. MANRICH, A. ; GALVÃO, Célia M A ; JESUS, C. D. F. ; GIORDANO, R. C. ; GIORDANO, R. L. C. . Immobilization of trypsin on chitosan gels: Use of different activation protocols and comparison with other supports. International Journal of Biological Macromolecules, v. online, p. 1-8, 2008.
16. GONÇALVES, L. R. B. ; Ferreira, A. L. O. ; Fernandez-Lafuente, R. ; GUISAN, J. M. ; Giordano, R. C. ; GIORDANO, R. L. C. . Influence of mass transfer limitations on the enzymatic synthesis of ?-lactam antibiotics catalyzed by penicillin G acylase immobilized on glioxil-agarose. Bioprocess and Biosystems Engineering, v. 31, p. 411-418, 2008.
17. PINOTTI, Laura M ; SOUZA, Vanessa R de ; GIORDANO, R. C. ; GIORDANO, R. L. C. . The Penicillin G Acylase Production by B. megaterium is Amino Acid Consumption Dependent. Biotechnology and Bioengineering, v. 97, p. 346-353, 2007.
18. NUCCI, Edson Romano ; SILVA, Rosineide Gomes da ; SOUZA, Vanessa R de ; GIORDANO, R. L. C. ; GIORDANO, R. C. ; CRUZ, A. J. G. . Comparing the performance of multilayer perceptrons networks and neuro-fuzzy systems for on-line inference of Bacillus megaterium cellular concentrations. Bioprocess and Biosystems Engineering, v. 30, p. 429-438, 2007.
19. PINTO, Gilson Alexandre ; GIORDANO, R. L. C. ; GIORDANO, R. C. . Neural Network Inference of Molar Mass Distributions of Peptides during Tailor-Made Enzymatic Hydrolysis of Cheese Whey: Effects of pH and Temperature. Applied Biochemistry and Biotechnology, v. 143, p. 142-152, 2007.
20. PINTO, Gilson Alexandre ; TARDIOLLI, Paulo Waldyr ; CABRERA-PADILLA, R. Y. ; GALVÃO, Célia M A ; GIORDANO, R. C. ; GIORDANO, R. L. C. . Amino acids yields during proteolysis catalyzed by carboxypeptidase A are strongly dependent on substrate pre-hydrolysis. Biochemical Engineering Journal, v. 39, p. 328-337, 2007.
21. FERREIRA, Andrea Lopes de Oliveira ; GIORDANO, R. L. C. ; GIORDANO, R. C. . Nonconventional Reactor for Enzymatic Synthesis of Semi-Synthetic -Lactam Antibiotics. Industrial & Engineering Chemistry Research, v. 46, p. 7695-7702, 2007.
22. GIORDANO, R. C. ; RIBEIRO, Marcelo Perencin de Arruda ; GIORDANO, Raquel de Lima Camargo . Kinetics of beta-lactam antibiotics synthesis by penicillin G acylase (PGA) from the viewpoint of the industrial enzymatic reactor optimization. Biotechnology Advances, v. 24, n. 1, p. 27-41, 2006.
23. Silva, R. G. ; Souza, V. R. ; Nucci, E. R. ; Pinotti, L. M. ; CRUZ, A. J. G. ; Giordano, R. C. ; Giordano, R. L.C. . Using a medium of free amino acids to produce penicillin g acylase in fed-batch cultivations of Bacillus megaterium ATCC 14945. Brazilian Journal of Chemical Engineering, v. 23, n. 1, p. 37-43, 2006.
24. GONÇALVES, Viviane Maimoni ; TAKAGI, Mickie ; CARNEIRO, Silvia Mendes ; GIORDANO, R. C. ; TANIZAKI, Martha . Introduction of air in the anaerobic culture of Streptococcus pneumoniae serotype 23F induces the release of capsular polysaccharide from bacterial surface into the cultivation medium. Journal of Applied Microbiology, v. 101, p. 1009-1014, 2006.
25. RESENDE, M. M. ; SOUSA JR, Ruy ; TARDIOLLI, Paulo Waldyr ; GIORDANO, Raquel de Lima Camargo ; GIORDANO, R. C. . Enzymatic tailor-made proteolysis of whey in a vortex flow reactor. AIChE Journal, EUA, v. 51, n. 1, p. 314-322, 2005.
26. GONÇALVES, Luciana R B ; GIORDANO, Raquel de Lima Camargo ; GIORDANO, R. C. . Mathematical modeling of batch and semibatch reactors for the enzymic synthesis of amoxicillin. Process Biochemistry (Cessou em 1990. Cont. c/ outro título e ISSN. Cessou novamente e voltou a ter o título anterior [Process Biochemistry]), UK, v. 40, n. 1, p. 247-256, 2005.
27. TARDIOLLI, Paulo Waldyr ; SOUSA JR, Ruy ; GIORDANO, R. C. ; GIORDANO, Raquel de Lima Camargo . Kinetic model of the hydrolysis of polypeptides catalyzed by Alcalase immobilized on 10%-glyoxyl-agarose. Enzyme and Microbial Technology, Grã-Bretanha, v. 36, n. 4, p. 555-564, 2005.
28. RIBEIRO, Marcelo Perencin de Arruda ; FERREIRA, Andrea Lopes de Oliveira ; GIORDANO, Raquel de Lima Camargo ; GIORDANO, R. C. . Selectivity of the enzymatic synthesis of ampicillin by E. coli PGA in the presence of high concentrations of substrates. Journal of Molecular Catalysis. B, Enzymatic, v. 33, n. 3, p. 81-86, 2005.
29. RIBEIRO, Marcelo Perencin de Arruda ; GIORDANO, R. C. . Variational Calculus (Optimal Control) Applied to the Optimization of the Enzymatic Synthesis of Ampicillin. Brazilian Archives of Biology and Technology, v. 48, p. 19-28, 2005.
30. PINTO, Gilson Alexandre ; SOUSA JR, Ruy ; GIORDANO, R. C. . Comparison of Performance of Different Algorithms innoisy signals filtering of process in enzymatic hydrolysisof cheese whey. Brazilian Archives of Biology and Technology, v. 48, p. 151-159, 2005.
31. SILVA, Rosineide Gomes da ; NUCCI, Edson Romano ; GOMES, T C ; GIORDANO, R. C. ; CRUZ, Antônio José Gonçalves da . A fuzzy logic algorithm for identification of the harvesting threshold during PGA production by Bacillus megaterium. Brazilian Journal of Chemical Engineering, São Paulo, v. 22, n. 04, p. 521-527, 2005.
32. CRUZ, A. J. G. ; PAN, T. ; GIORDANO, R. C. ; ARAUJO, Maria Lucia G.c. ; HOKKA, C. O. . Cephalosporin C production by immobilized Cephalosporium acremonium cells in a repeated batch tower bioreactor. Biotechnology and Bioengineering, New York, v. 85, n. 1, p. 96-102, 2004.
33. SOUSA JR, Ruy ; LOPES, G. P. ; TARDIOLLI, Paulo Waldyr ; GIORDANO, Raquel de Lima Camargo ; ALMEIDA, P. I. F. ; GIORDANO, R. C. . Kinetic model for whey protein hydrolysis by alcalase multipoint-immobilized on agarose gel particles. Brazilian Journal of Chemical Engineering, São Paulo, v. 21, n. 02, p. 147-154, 2004.
34. RESENDE, M. M. ; VIEIRA, P. G. ; SOUSA JR, Ruy ; GIORDANO, Raquel de Lima Camargo ; GIORDANO, R. C. . Estimation of mass transfer parameters in a Taylor-Couette-Poiseuille heterogeneous reactor. Brazilian Journal of Chemical Engineering, São Paulo, v. 21, n. 02, p. 175-184, 2004.
35. SOUSA JR, Ruy ; LOPES, G. P. ; PINTO, Gilson Alexandre ; ALMEIDA, P. I. F. ; GIORDANO, R. C. . GMC-fuzzy control of pH during enzymatic hydrolysis of cheese whey proteins. Computers and Chemical Engineering, Reino Unido, v. 28, n. 9, p. 1661-1672, 2004.
36. FERREIRA, Andrea Lopes de Oliveira ; GIORDANO, Raquel de Lima Camargo ; GIORDANO, R. C. . Improving the selectivity and productivity of enzymatic synthesis of ampicillin with immobilized penicillin G acylase. Brazilian Journal of Chemical Engineering, São Paulo, v. 21, n. 4, p. 519-529, 2004.
37. SOUSA JR, Ruy ; RESENDE, M. M. ; GIORDANO, Raquel de Lima Camargo ; GIORDANO, R. C. . Hybrid model for an enzymatic reactor: hydrolysis of cheese whey proteins by alcalase immobilized in agarose gel particles. Applied Biochemistry and Biotechnology, v. 105-08, n. 03, p. 413-422, 2003.
38. GONÇALVES, Luciana R B ; FERNANDEZLAFUENTE, R. ; GUISAN, J. M. ; GIORDANO, R. L. C. ; GIORDANO, R. C. . Inhibitory effects in the side reactions occurring during the enzymatic synthesis of amoxicillin: P-hydroxyphenylglycine methyl ester and amoxicillin hydrolysis. Biotechnology and Applied Biochemistry, v. 38, n. 1, p. 77-85, 2003.
39. GONÇALVES, Viviane Maimoni ; TAKAGI, Mickie ; LIMA, R. B. ; MASSALDI, H. ; RAW, I. ; GIORDANO, R. C. ; TANIZAKI, Martha . Purification of capsular polysaccharide from Streptococcus pneumoniae serotype 23F by a simple and efficient method. Biotechnology and Applied Biochemistry, Reino Unido, v. 37, p. 283-287, 2003.
40. RESENDE, M. M. ; RATUSZNEI, S. M. ; SUAZO, C. A. T. ; GIORDANO, R. C. . Simulating a ceramic membrane bioreactor for the production of penicillin: an example of the importance of consistent initialization for solving DAE systems. Process Biochemistry (Cessou em 1990. Cont. c/ outro título e ISSN. Cessou novamente e voltou a ter o título anterior [Process Biochemistry]), Reino Unido, v. 37, n. 11, p. 1297-1305, 2002.
41. GONÇALVES, Luciana R B ; SOUSA JR, Ruy ; FERNANDEZLAFUENTE, R. ; GUISAN, J. M. ; GIORDANO, R. L. C. ; GIORDANO, R. C. . Enzymatic synthesis of amoxicillin: avoiding limitations of the mechanistic approach for reaction kinetics. Biotechnology and Bioengineering, New York, v. 80, n. 6, p. 622-631, 2002.
42. GONÇALVES, Viviane Maimoni ; ZANGIROLAMI, Teresa Cristina ; GIORDANO, R. L. C. ; RAW, I. ; TANIZAKI, Martha ; GIORDANO, R. C. . Optimization of medium and cultivation conditions for capsular polysaccharide production by Streptococcus pneumoniae serotype 23 F. Applied Microbiology and Biotechnology, Berlin, v. 59, n. 6, p. 713-717, 2002.
43. PINOTTI, Laura M ; SILVA, Rosineide Gomes da ; GIORDANO, R. C. ; GIORDANO, Raquel de Lima Camargo . Inoculum studies in production of penicillin G acylase by Bacillus megaterium ATCC14945. Applied Biochemistry and Biotechnology, Totowa, EUA, v. 98-100, p. 679-689, 2002.
44. RESENDE, M. M. ; TARDIOLLI, Paulo Waldyr ; FERDANDEZ, V. M. ; FERREIRA, Andrea Lopes de Oliveira ; GIORDANO, Raquel de Lima Camargo ; GIORDANO, R. C. . Distribution of Suspended Particles in a Taylor-Poiseuille Vortex Flow Reactor. Chemical Engineering Science, Reino Unido, v. 56, n. 3, p. 755-761, 2001.
45. CRUZ, Antônio José Gonçalves da ; ALMEIDA, Renata M R G ; ARAUJO, M. L. G. C. ; GIORDANO, R. C. ; HOKKA, Carlos O. . The dead core model applied to beads with immobilized cells in a fed-batch cephalosporin C production bioprocess. Chemical Engineering Science, Reino Unido, v. 56, n. 2, p. 419-425, 2001.
46. SILVA, Rosineide Gomes da ; CRUZ, A. J. G. ; HOKKA, Carlos O. ; GIORDANO, Raquel de Lima Camargo ; GIORDANO, R. C. . A hybrid neural network algorithm for on-line state inference that accounts for differences in inoculum of cephalosporium acremonium in fed-batch fermentors. Applied Biochemistry and Biotechnology, Estados Unidos, v. 91-93, p. 341-352, 2001.
47. CRUZ, A. J. G. ; ARAUJO, Maria Lucia G.c. ; GIORDANO, R. C. ; HOKKA, Carlos O. . Modeling and simulation of cephalosporin c production in a fed-batch tower-type bioreactor. Applied Biochemistry and Biotechnology, Estados Unidos, v. 91-93, p. 537-549, 2001.
48. GONÇALVES, L. R. B. ; SUZUKI, G. ; GIORDANO, R. C. ; GIORDANO, Raquel de Lima Camargo . Kinetic and mass transfer parameters of maltotriose hydrolysis catalyzed by gluoamylase immobilized on macroporous silica and wrapped in pectin gel. Applied Biochemistry and Biotechnology, Estados Unidos, v. 91-93, p. 691-702, 2001.
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